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Consideration should be given to changing the therapeutic regimenincluding possibly retin-a. discontinuing the medicationin patients whose depression is persistently worseor who are experiencing emergent suicidality or symptoms that might be precursors to worsening depression or suicidalityespecially if these symptoms are severeabrupt in onsetor were not part of the patient’s presenting symptoms.
The only commonly observed adverse event that occurred in Celexa patients with an incidence of 5or greater and at least twice the incidence in placebo patients was ejaculation disorderprimarily ejaculatory delayin male patientssee TABLE 3
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