Results from a crossover study in healthy subjects have shown a pharmacokinetic interaction between clopidogrel 300 mg loading dose 75 mg daily maintenance dose and esomeprazole 40 mg p.
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The effect of gemfibrozil in pregnant women has not been well-studiedGemfibrozil should be used during pregnancy only if the potential benefit justifies the unknown but potential risk to the fetus.
The list of product names concerned is given in Annex IThe scientific conclusions are provided in Annex II together with the amended SPC in Annex III.
Musculoskeletaljointbackor muscle painmyastheniamyopathysynovitismyositisrhabdomyolysis.
Otherabnormal tastechillsweight lossincreased risk of bacterial and viral infectionlupuslike syndromeanaphylaxis.
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